John Boulos, Ph.D.

John Boulos, Ph.D.

Professor of Chemistry

Ph.D. in Organic Chemistry, Graduate School of CUNY, 1991.
M. Phil. in Organic Chemistry, Graduate School of CUNY, 1990.
BA in Chemistry, Queens College / CUNY, 1985.

Joined Barry: January 1992.

Courses

  • CHE 111, CHE 111L General Chemistry and Qualitative Analysis with Lab, I
  • CHE 112, CHE 112L General Chemistry and Qualitative Analysis with Lab, II
  • CHE 152, CHE 152L Introduction to Organic and Biological Chemistry with Lab
  • CHE 343, CHE 343L Organic Chemistry with Lab, I
  • CHE 344, CHE 344L Organic Chemistry with Lab, II
  • CHE 352, CHE 352L Biochemistry I with Lab
  • CHE 353 Biochemistry II
  • CHE 449 Advanced Spectroscopy
  • CHE 356/357 Physical Chemistry I and II
  • CHE 395, CHE 495 Research

Research Interests

  • Synthesis of novel and functionally selective muscarinic agonists and antagonists for Alzheimer's, Parkinson, Schizophrenia and COPD applications.

Selected Publication

  • Boulos J, Jakubik J, Randakova A, Rudajev V, Dolezal V. Novel Long-Acting Antagonists of Muscarinic Acetylcholine Receptors, British Journal of Pharmacology, 2018 (accepted)
  • Boulos J, Jakubik J, Randakova A, Boulos JM, Momirov J. Synthesis of Novel and Functionally Selective Non-competitive Muscarinic Antagonists as Chemical Probes, Chem Biol Drug Des., 91 (1), 93-104, 2018
  • Issued U.S. and International Utility Patent- Bitopic muscarinic agonists and antagonists and methods of synthesis and use thereof, 2015
  • Provisional U.S. Patent- Discovery and synthesis of functionally selective partial muscarinic agonists for treatment of human diseases, 2015
  • Boulos J, Jakubik J, Randakova A, Avila C. Synthesis of N- Substituted Piperidine Salts as Potential Muscarinic Ligands for Alzheimer’s Applications, J. Heterocyclic. Chem., 50 (6), 1363, 2013

Selected Conference Presentations

  • John F. Boulos, Jocelyn Baquier Synthesis and biological evaluation of novel long acting muscarinic antagonists, 255th American Chemical Society National Meeting, New Orleans, LA, March 18-22, 2018; 10th Annual STEM Research Symposium, Barry University, FL, April 6, 2018
  • Momirov, J.; Boulos, J. Synthesis of functionally selective M1/M4 antagonist for Parkinson’s disease application SoFL-ACS Chemical Sciences Symposium; 2017 Feb 26; Nova Southeastern University, Ft. Lauderdale, FL; 9th Annual STEM Research Symposium, Barry University, FL, April 12, 2017
  • Peter Nwokoye, John Boulos Thiophene-N-Substituted Tetrahydropyridinyl Salts as Functionally Selective Muscarinic Agonists 249th ACS National meeting, Denver, CO, March 22-26, 2015. 7th Annual STEM Research Symposium (winning poster), Barry University, FL, April 2015
  • Hangny Dao, John Boulos, and Jan Jakubik Synthesis of bitopic muscarinic antagonists and functionally selective agonists for pharmaceutical applications 247th American Chemical Society National Meeting, Dallas, TX, March 16-20, 2014; 6th Annual STEM Research Symposium (winning poster), Barry University, FL, April 16, 2014; 2014 Florida Annual Meeting and Exposition, American Chemical Society, Innisbrook, FL, May 8-10, 2014
  • Rhony F. Jean and John Boulos Synthesis of 2-thiophene-N-tetrahydropyridium methyliodide salt of muscarinic M1 and M4 ligands for psychological treatment of Schizophrenia 245th American Chemical Society National Meeting, New Orleans, LA, April 7-11, 2013; 5th Annual STEM Research Symposium, Barry University, FL, March 27, 2013

Honors / Awards

  • The Apple Award, Office of Commuter Affairs, Barry University, 2003
  • Outstanding Teaching Award, Barry Student Honor Society, 1995

Professional Memberships

  • American Chemical Society
  • Gamma Sigma Epsilon, Chemistry Honor Society
  • Sigma Xi, the Scientific Research Society

Contact Information

Office: Wiegand 124
Telephone: 305-899-3432
Fax: 305-899-3479
E-mail: jboulos@barry.edu