Conrad Fischer, PH.D

Conrad Fischer, PH.D

Assistant Professor of Chemistry

PH.D. In Chemistry, Department Of Chemistry, Technical University Freiberg, Freiberg, Germany, 2012
M.SC. (DIPL.-CHEM.) In Chemistry, Graduated With Honors, Department Of Chemistry, Technical University Freiberg, Freiberg, Germany, 2008

Joined Barry: January 2021.

Courses

  • CHE 343, CHE 343L Organic Chemistry with Lab, I
  • CHE 344, CHE 344L Organic Chemistry with Lab, II
  • CHE 352, CHE 352L Biochemistry I with Lab
  • CHE 395, CHE 495 Research

Research Interests

  • Cardiovascular active peptides and GPCR receptor signaling
  • Viral protease inhibitors
  • Nature-inspired supramolecular inclusion hosts

Selected Publications

  • Fischer, C.; Lamer, T.; Fernandez, K.; Gheblawi, M.; Wang, W.; Pascoe, C.; Lambkin, G.; Iturrioz, X.; Llorens-Cortes, C.; Oudit, G.Y.; Vederas, J.C. Optimizing PEG-extended apelin analogues as cardioprotective drug leads. Importance of the KFRR motif and aromatic head group for improved physiological activity. J. Med. Chem., 63, 12073-12082, 2020
  • Vuong, W.; Khan, M.B.; Fischer, C.; Arutyunova, E.; Lamer, T.; Shields, J.; Bandi, H.; McKay, R.T.; van Belkum, M.J.; Joyce, M.; Young, H.S.; Tyrrell, L.; Vederas, J.C.; Lemieux, M. J. Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication, Nature Commun., 11, 4282, 2020
  • Fischer, C. A patent review of apelin receptor modulators (2014-2019), Expert Opin. Ther. Pat., 30, 251-261, 2020
  • Masoud, A.G.T.; Lin, J.X.; Farhan, M.A.; Fischer, C.; Zhu, L. F.; Anderson, C. C.; Sis, B.; Kassiri, Z.; Moore, R. B.; Kim, D.; Vederas, J. C.; Adam, B. A.; Oudit, G. Y.; Murray, A. G. Apelin directs endothelial cell differentiation and vascular repair following immune-mediated injury, J. Clin. Invest., 130, 94-107, 2020

Selected Conference Presentations

  • Apelin analogues as novel cardioprotective drugs, 102nd Canadian Chemistry Conference and Exhibition, June 2019, Quebéc, Canada
  • PEGylated apelin analogues as cardiovascular active drugs, 101st Canadian Chemistry Conference and Exhibition, May 2018, Edmonton, Canada
  • Apelin as key peptide for heart disease treatment, 1st RSC Anglo-Nordic Medical Chemistry Symposium, June 2017, Snekkersten Conference Center, Helsingør, Denmark
  • Engineered apelin and natriuretic peptides as potent therapeutics for the treatment of cardiovascular diseases. Invited talk, June 2017, University of Lincoln, Lincoln, UK
  • Apelin as key peptide for heart disease treatment. 34th European Peptide Symposium, September 2016, University of Leipzig, Leipzig, Germany
  • Laterally modified calix[4]arenes as potential sensor materials. 20th Junior Research-Symposium in Bioorganic chemistry, September 2011, KIT Karlsruhe, Karlsruhe, Germany

Honors / Awards

  • 2016-2018 Postdoctoral Fellowship, Alberta Innovates Health Solutions
  • 2014-2015 Postdoctoral Fellowship, Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)
  • 2008 M.Sc. thesis award, Agricola Medal and Price for best MSc thesis in 2008, University Freiberg, Germany

Professional Memberships

  • ACS – American Chemical Society, 2021-present
  • CSC – Canadian Society of Chemistry, 2018-present
  • GDCh – German Chemical Society, 2008-present

Contact Information

Office: Wiegand 128A
Telephone: 305-899-3430
Fax: 305-899-3479
E-mail: cfischer@barry.edu